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. 2021 Sep 17;12:702360. doi: 10.3389/fphar.2021.702360

TABLE 3.

A list of histone arginine methyltransferase inhibitors under different phases of clinical trial and their indication.

Histone arginine methyltransferase inhibitor
Classification Compounds Structure Clinical stage References
PRMT1 DB75 graphic file with name fphar-12-702360-fx15.jpg Preclinical Oudard et al. (2017)
PRMT4 TP064 graphic file with name fphar-12-702360-fx16.jpg Preclinical Loe et al. (2021)
PRMT5 EPZ015938 (GSK3326595) graphic file with name fphar-12-702360-fx17.jpg Clinical Li et al. (2019)