TABLE 3.
A list of histone arginine methyltransferase inhibitors under different phases of clinical trial and their indication.
| Histone arginine methyltransferase inhibitor | ||||
|---|---|---|---|---|
| Classification | Compounds | Structure | Clinical stage | References |
| PRMT1 | DB75 |
|
Preclinical | Oudard et al. (2017) |
| PRMT4 | TP064 |
|
Preclinical | Loe et al. (2021) |
| PRMT5 | EPZ015938 (GSK3326595) |
|
Clinical | Li et al. (2019) |