Table 2.
Cognitive function of study participants grouped according to the SUVr of amyloid PET and the presence of rs671 A allele (N = 179).
Cognitive function (Z-score) | A(−) (SUVr < 0.65) | A(+) (SUVr > 0.65) | Pa | Post-hoc | ||
---|---|---|---|---|---|---|
AC (N = 25) | GG (N = 62) | AC (N = 31) | GG (N = 61) | |||
Mean (SD) | Mean (SD) | Mean (SD) | Mean (SD) | |||
Attention function | − 0.454 (0.931) | − 0.070 (0.906) | − 0.526 (1.026) | − 0.499 (1.129) | 0.073 | |
Language function | − 0.616 (1.891) | − 0.498 (1.416) | − 1.228 (2.286) | − 1.137 (2.055) | 0.188 | |
Visuospatial function | − 1.114 (1.905) | − 0.665 (1.472) | − 1.856 (3.380) | − 2.224 (2.663) | 0.003 | 2 > 4 |
Memory function | − 0.952 (1.459) | − 1.054 (1.196) | − 2.292 (1.459) | − 2.222 (1.573) | < 0.001 | 1 > 3, 2 > 4 |
Frontal/executive function | − 1.569 (2.004) | − 0.875 (1.467) | − 2.166 (2.359) | − 2.515 (2.183) | < 0.001 | 2 > 4 |
AC, A-carrier; PET, positron emission tomography SD, standard deviation; SUVr, standardized uptake value ratio.
All values are z-score results.
aANOVA test was conducted for continuous variables.