Table 3.

Results of regressions analyses of the interaction effect of amyloid deposition and rs671 polymorphism on brain cortical thickness, only showing significant regions.

Regions	Estimatea	Standard errora	Unadjusted P	FDR corrected P
Lt. cuneus	− 0.143	0.049	0.004	0.043
Lt. pars opercularis	− 0.162	0.047	0.001	0.038
Lt. pars triangularis	− 0.134	0.045	0.004	0.043
Lt. rostral middle frontal	− 0.162	0.049	0.001	0.038
Lt. superior parietal	− 0.145	0.045	0.002	0.038
Lt. insula	− 0.186	0.066	0.005	0.047
Rt. inferior parietal	− 0.152	0.055	0.006	0.048
Rt. pars triangularis	− 0.163	0.055	0.004	0.043
Rt. superior parietal	− 0.139	0.048	0.005	0.045

FDR, false discovery rate; APOE, apolipoprotein E; CDR, clinical dementia rating.

Adjusted for age, sex, education year, total intracranial volume, APOE-ε4 carrier status, lifetime drinking status, Framingham general cardiovascular risk score, CDR sum of box, white matter hyperintensity score of peripheral and deep white matter.

^aValues from amyloid deposition and rs671 polymorphism interaction term in multiple regression model.