Table 1.
Baseline and clinical characteristics of the study population.
| Variables | Thrombocytopenia N = 696 | Non-thrombocytopenia N = 4,219 | P |
|---|---|---|---|
| Age, years | 73.6 (65.9, 80.0) | 67.6 (59.6, 75.4) | <0.001 |
| Gender, male, n (%) | 477 (68.5%) | 3,180 (75.4%) | <0.001 |
| BMI | 26.5 (23.6, 29.9) | 28.2 (25.1, 31.9) | <0.001 |
| Comorbidities | |||
| Hypertension, n (%) | 515 (74.0%) | 3,174 (75.2%) | 0.479 |
| Congestive heart failure, n (%) | 223 (32.0%) | 1,045 (24.8%) | <0.001 |
| Diabetes, n (%) | 220 (31.6%) | 1,667 (39.5%) | <0.001 |
| Chronic pulmonary disease, n (%) | 88 (12.6%) | 625 (14.8%) | 0.146 |
| Renal failure, n (%) | 75 (10.8%) | 419 (9.9%) | 0.496 |
| Laboratory tests | |||
| WBC, 109/L | 12.1 (9.4, 15.0) | 14.0 (11.1, 17.5) | <0.001 |
| Platelet, 109/L | 84 (71, 92) | 155 (128, 191) | <0.001 |
| Hemoglobin, g/L | 76 (67, 87) | 86 (75, 97) | <0.001 |
| Lactate, mmol/L | 3.2 (2.2, 4.4) | 2.4 (1.9, 3.2) | <0.001 |
| Creatinine, mg/dl | 1.0 (0.8, 1.2) | 0.9 (0.8, 1.2) | 0.012 |
| APTT, seconds | 47.1 (37.0, 65.2) | 37.0 (31.6, 48.2) | <0.001 |
| PT, seconds | 16.7 (15.5, 18.4) | 15.2 (14.3, 16.3) | <0.001 |
| Vital signs | |||
| Heart rate, bpm | 84.9 (79.2, 90.0) | 84.7 (78.9, 90.9) | 0.966 |
| MAP, mmHg | 74.3 (70.6, 78.2) | 74.2 (70.6, 78.4) | 0.633 |
| Respiratory rate, bpm | 16.1 (14.6, 18.1) | 16.9 (15.3, 18.8) | <0.001 |
| Temperature, °C | 37.7 (37.3, 38.1) | 37.6 (37.2, 38.1) | 0.04 |
| Elective surgery, n (%) | 263 (37.8%) | 1,509 (35.8%) | 0.307 |
| SOFA score | 6 (5,8) | 4 (3,6) | <0.001 |
| SOFA score>2, n (%) | 685 (98.4%) | 3,298 (78.2%) | <0.001 |
Values are expressed as median (interquartile range), or n (%).
BMI, body mass index; WBC, white blood cell; APTT, activated partial thromboplastin time; PT, prothrombin time; MAP, mean arterial pressure; SOFA, sequential organ failure assessment.
In bold are statistically significant values.