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. 2021 Sep 17;12:748772. doi: 10.3389/fphar.2021.748772

TABLE 3.

Summary of potential metabolites in the serum.

No Metabolites Formula Retention time (min) Mass (m/z) Fold changea p value VIP valueb
Con vs. IMQ IMQ vs. ESW Con vs. IMQ IMQ vs. ESW Con vs. IMQ IMQ vs. ESW
1 Myo-inositolc C6H12O6 29.16 313.39 1.43 1.27 0.01 0.01 1.95 1.15
2 Z,Z-9,12-Octadecadienoic acidd C18H32O2 32.23 339.40 1.62 1.28 0.02 0.47 1.06 0.26
3 Cholesterold C27H46O 42.00 129.10 1.61 0.99 0.00 0.97 2.01 0.12
4 d-Galactosec C6H12O6 25.97 179.17 0.46 6.94 0.02 0.00 1.01 1.24
5 d-Mannosee C6H12O6 26.20 321.30 1.15 1.82 0.88 0.02 0.01 1.62
6 D-Glucosee C6H12O6 28.76 204.20 0.40 3.33 0.03 0.03 0.99 1.12
a

Fold change with a value >1 indicated a relatively higher intensity, whereas a value <1 indicated a relatively lower intensity.

b

VIP value was obtained from the OPLS-DA model.

c

Variables were obtained by comparing IMQ vs. Con and ESW (VIP >1 and p < 0.05).

d

Variables were obtained by comparing Con vs. IMQ (VIP >1 and p < 0.05).

e

Variables were obtained by comparing IMQ vs. ESW (VIP >1 and p < 0.05).