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. 2021 Sep 17;12:723393. doi: 10.3389/fimmu.2021.723393

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Copyright © 2021 Théroude, Reverte, Heinonen, Ciarlo, Schrijver, Antonakos, Maillard, Pralong, Le Roy and Roger

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Training for 9 weeks increases blood inflammatory monocytes and PMNs. (A) Blood counts of CD45⁺ leukocytes, Ly6C^low, Ly6C^lint and Ly6C^high monocytes (CD11b⁺Ly6G^-), PMNs (Ly6G⁺), T cells (CD3⁺) and B cells (B220⁺) in control mice (n = 10) and mice trained for 9 weeks (n = 8). Data are from 2 independent experiments. (B) Blood concentrations of IL-1β, IL-6, IL-12p40 and TNF in control mice and mice trained 1-9 weeks before analysis (n = 6 mice/group). Each dot represents a mouse. Lines represent mean and SD. The dotted horizontal lines in B represent median and limit of detection. P values reaching statistical significance are given in the graphs.