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. 2021 Sep 30;11:19500. doi: 10.1038/s41598-021-98659-5

Table 2.

Percentage of growth inhibition at 24 h of CAS and CAS in combination with H5K1.

Drug µg/ml CAS CAS in combination with:
0.25 µg/ml H5K1 2.5 µg/ml H5K1 25 µg/ml H5K1 250 µg/ml H5K1
4 90.3 89.7 89.6 89.6 94.5
2 93.1 93.3 93.1 93.0 94.2
1 94.5 94.7 94.6 94.8 95.7
0.5 95.8 95.7 95.9 95.8 96.1
0.25 90.4 94.4 96.0 95.8 96.2
0.125 79.0 94.0 93.1 93.1 94.0
0.0625 68.1⁎ 69.1⁎ 77.1⁎ 80.4⁎ 79.3⁎
0.03125 16.5 15.6 15.4 18.9 23.8
0.0156 11.9 12.6 9.8 11.3 13.3
0.0078 11.5 11.0 9.9 11.7 10.8

The MIC50 breakpoints are marked with *.