. 2021 Sep 14;2(9):100397. doi: 10.1016/j.xcrm.2021.100397

Table 2.

Hierarchical multivariate analysis for the predictors of hepatic fat (age, gender, cold-induced percentage decline in SCV PDFF, total body fat, and visceral adipose tissue)

	Coefficients							Model
	N	B	SE	β	95% CI		p	R²	adjusted R²	p
	N	B	SE	β	lower bound	upper bound	p	R²	adjusted R²	p
Model 1A (+ cold-induced percentage decline in SCV PDFF)	59							0.338	0.289	< 0.001^∗

Age (years)		0.085	0.049	0.221	−0.013	0.183	0.087
Gender (male)		0.430	0.899	0.056	−1.373	2.233	0.635
Cold-induced percentage decline in SCV PDFF (%)		−1.153	0.318	−1.172	−1.790	−0.516	0.001^∗
Cold-induced percentage decline in SCV PDFF (%)²		0.067	0.023	0.896	0.020	0.113	0.006^∗

Model 1B (+ body fat percentage)	59							0.433	0.380	< 0.001^∗

Age (years)		0.051	0.047	0.132	−0.043	0.145	0.284
Gender (male)		1.256	0.885	0.164	−0.519	3.031	0.162
Cold-induced percentage decline in SCV PDFF (%)		−0.885	0.310	−0.900	−1.507	−0.264	0.006^∗
Cold-induced percentage decline in SCV PDFF (%)²		0.061	0.022	0.822	0.018	0.105	0.007^∗
Body fat (%)		0.129	0.043	0.435	0.042	0.216	0.004^∗

Model 2B (+ VAT)	56							0.504	0.454	< 0.001^∗

Age (years)		−0.013	0.061	−0.030	−0.135	0.109	0.836
Gender (male)		−0.336	0.845	−0.043	−2.033	1.360	0.692
Cold-induced percentage decline in SCV PDFF (%)		−0.760	0.309	−0.769	−1.380	−0.139	0.017^∗
Cold-induced percentage decline in SCV PDFF (%)²		0.051	0.022	0.690	0.008	0.095	0.021^∗
VAT (cm²)		0.081	0.022	0.556	0.036	0.126	0.001^∗

Quadratic function of cold-induced percentage decline in SCV PDFF (%) was used, as it fits better than the linear model (linear R² = 0.173 versus quadratic R² = 0.301). SCV, supraclavicular; PDFF, proton density fat fraction; VAT, visceral adipose tissue.

^∗

p < 0.05.