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. 2021 Sep 17;9:724310. doi: 10.3389/fcell.2021.724310

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Copyright © 2021 Zhang, Huang, Fu, Liu, Wang, Wang, Qu, Li, Fan, Hu and Miao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of differentially expressed genes in control-2D vs. dihydrotestosterone-2D and control-3D vs. dihydrotestosterone-3D, and the expression of proven genes. Volcano plot used to determine the DEGs in control-2D vs. DHT-2D (A) and control-3D vs. DHT-3D (C) using the following criteria: p < 0.05 and log2| FC| > 1. Heatmap depicting the expression of six genes in control-2D vs. DHT-2D (B) and control-3D vs. DHT-3D (D). Red indicates upregulation and blue indicates downregulation. (E) Quantity of DEGs in control-2D vs. DHT-2D and control-3D vs. DHT-3D. Blue represents upregulation and green represents downregulation. DEGs, differentially expressed genes; DHT, dihydrotestosterone.