TABLE 1.

The biological functions of USP47.

Interactors	Functional outcomes	References
Katanin	Promoting the Katanin-p60-mediated axonal growth in hippocampal neurons	Yang et al., 2013
KIFC3	Maintaining stable cell-cell adhesion by suppressing the E-cadherin degradation	Sako-Kubota et al., 2014
Polβ	Base excised repair pathway, repair damage DNA	Weinstock et al., 2012
IK	Increasing the level of ATM through IK deubiquitination	Ka et al., 2020
β-TrCP	Significance unclear; promotes USP47 ubiquitination; inhibit β-TrCP degradation, modulation of Gli transcription factors	Peschiaroli et al., 2010; Shi et al., 2015; Bufalieri et al., 2019
YAP	Stabilization of YAP contributes to the progression of colorectal cancer	Pan et al., 2020
Snail	Promoting EMT	Choi et al., 2017
SATB1	Promoting colorectal cancer proliferation, migration, tumorigenesis, and resistance to 5-FU	Yu et al., 2019
RPS2	Inhibiting the interaction between RPS2 and MDM2, promoting P53 wild-type colorectal cancer proliferation and clone formation	Cho et al., 2020
β-catenin	Activating Wnt signaling pathway	Shi et al., 2015
YB-1	DNA damage repair	Lei et al., 2021
NLRP3	Regulating the activity of inflammatory bodies in macrophages	Palazón-Riquelme et al., 2018