Table 1.
Parameters | Blood | Tissue | |||||
---|---|---|---|---|---|---|---|
Healthy donors | CD patients | ||||||
Untreated | Remission | Failure | Untreated | Remission | Failure | ||
Average age (mín.–max.) | 32 (23–41) | 24 | 35 (19–50) | 39 (19–63) | 28 (19–49) | 43 (17–44) | 38 (61–16) |
Standard deviation (age) | 10.11 | 0.00 | 12.14 | 14.65 | 13.96 | 3.51 | 31.81 |
Females | 3 | 1 | 8 | 5 | 3 | 2 | 0 |
Males | 2 | 0 | 4 | 7 | 1 | 1 | 2 |
Total | 5 | 1 | 12 | 11 | 4 | 3 | 2 |
Medications | |||||||
Corticosteroids | – | – | – | 3 (27.3%) | 1 (25%) | – | 1 (50%) |
Mesalazine | – | 1 (100%) | 3 (25%) | 6 (54.6%) | 2 (50%) | 2 (66.6%) | 1 (50%) |
Azathioprine | – | – | 3 (25%) | 4 (36.4%) | 3 (75%) | – | 2 (100%) |
Anti-diarrheic | – | – | 1 (8.3%) | 1 (9.1%) | – | 1 (33.3%) | – |
Antidepressants | 2 (40%) | – | 2 (16.6%) | – | – | 1 (33.3%) | 1 (50%) |
Antibiotics | – | – | – | 2 (18.2%) | 1 (25%) | – | – |
Hepatics and pancreatics | – | – | – | 3 (27.3%) | 1 (25%) | – | 1 (50%) |
Hepatics and Hidrocortisone pre-IFXb | – | – | – | 1 (9.1%) | – | – | – |
Other | 2 (40%) | 1 (100%) | 2 (16.6%) | 4 (36.4%) | 2 (50%) | 1 (33.3%) | 2 (100%) |
aCD, Crohn’s disease; bIFX, infliximab.