FIGURE 2.

In situ imaging evaluations of reconstructed ureteral conduits. Representative data for Pigs 1–5. Ureters were implanted with stented, tubular BLSF matrices. Stents were removed at 8 weeks post-op and swine were harvested at 3 months. In the majority of swine, severe Grade 4 hydronephrosis and neotissue stricture formation were detected in operated ureters at sacrifice. X-Ray (2, 4, 8 weeks) and contrast RUPG (12 weeks) (top rows); sonograms (bottom rows with hydronephrosis scores); and URS (insets showing regenerated mucosa) assessments were performed at various experimental timepoints. STR, stricture and RUPG, retrograde ureteropyelogram.