Table 2.
Concentrations of sKlotho protein and selected adhesion molecules in children with type 1 diabetes according to diabetes duration.
| sKlotho [pg/mL] | sICAM-1 [ng/mL] | sVCAM-1 [ng/mL] | E-Selectin [ng/mL] | |
|---|---|---|---|---|
| Mean (SD) (min, max) | Mean (SD) (min, max) | Mean (SD) (min, max) | Mean (SD) (min, max) | |
| <2 months (N = 19) | 1824.9 (1211.4) (880.5, 5482.2) | 299.9 (50.5) (214.7, 416.1)* | 682.9 (162.1) (364.6, 908.2) | 54.9 (18.5) (29.7, 102.1)* |
| 2 months - 2 years (N = 20) | 2150.0 (967.1) (976.0, 4306.9) | 236.1 (22.5) (176.3, 267.8)* | 634.9 (108.2) (471.5, 844.5) | 48.1 (17.3) (29.9, 80.1) |
| 2-5 years (N = 20) | 1977.4 (873.7) (753.3, 3445.9) | 269.1 (73.9) (136.1, 453.5) | 634.9 (112.0) (443.2, 874.5) | 39.1 (14.5) (19.5, 74.3)* |
| >5 years (N = 21) | 2187.2 (1036.9) (733.4, 4217.5) | 270.9 (80.3) (169.1, 496.7) | 628.7 (246.0) (361.0, 1464.2) | 40.4 (13.6) (20.6, 78.4) |
| P | >0.05 | 0.0075 | >0.05 | 0.0139 |
| P (post-hoc test) | 0.0129 | 0.0284 |
*Variables that are statistically significantly different are marked with an asterisk.