Table 3.
Spearman rank correlation coefficients between sKlotho protein, studied adhesion molecules and selected risk factors in children with type 1 diabetes.
| sKlotho | sICAM-1 | sVCAM-1 | E-selectin | |
|---|---|---|---|---|
| r (P value) | r (P value) | r (P value) | r (P value) | |
| Age | -0.09 (>0.05) | -0.34 (0.0038) | -0.17 (>0.05) | -0.40 (0.0006) |
| T1D duration | 0.18 (>0.05) | -0.01 (>0.05) | -0.13 (>0.05) | -0.24 (>0.05) |
| HbA1c [%] | -0.31 (0.0066) | -0.01 (>0.05) | 0.01 (>0.05) | 0.25 (0.0351) |
| Total cholesterol | 0.31 (0.0129) | -0.06 (>0.05) | 0.06 (>0.05) | 0.05 (>0.05) |
| HDL cholesterol | 0.43 (0.0011) | 0.11 (>0.05) | 0.19 (>0.05) | -0.06 (>0.05) |
| LDL cholesterol | 0.28 (0.0412) | -0.1 (>0.05) | 0.01 (>0.05) | -0.06 (>0.05) |
| Triglycerides | -0.18 (>0.05) | -0.05 (>0.05) | -0.08 (>0.05) | 0.23 (>0.05) |
| Serum creatinine | 0.10 (>0.05) | -0.26 (0.0469) | -0.21 (>0.05) | -0.36 (0.0074) |
| Albuminuria | 0.24 (>0.05) | -0.01 (>0.05) | -0.03 (>0.05) | -0.08 (>0.05) |
| AVBG | 0.03 (>0.05) | -0.09 (>0.05) | -0.12 (>0.05) | -0.22 (>0.05) |
| Blood glucose SD | 0.15 (>0.05) | -0.05 (>0.05) | -0.19 (>0.05) | -0.20 (>0.05) |
| TDD | -0.07 (>0.05) | -0.29 (>0.05) | -0.20 (>0.05) | -0.49 (0.0281) |
| E-selectin | -0.13 (>0.05) | 0.21 (>0.05) | 0.16 (>0.05) | - |
| sICAM-1 | 0.11 (>0.05) | - | 0.41 (0.0002) | 0.21 (>0.05) |
| sVCAM-1 | 0.11 (>0.05) | 0.41 (0.0002) | - | 0.16 (>0.05) |
| sKlotho | - | 0.11 (>0.05) | 0.11 (>0.05) | -0.13 (>0.05) |
T1D, type 1 diabetes; AVBG, average blood glucose; SD, standard deviation; TDD, total daily dose of insulin.