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. 2021 Sep 17;9:736603. doi: 10.3389/fcell.2021.736603

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Copyright © 2021 Guo, Hong, Zhang, Wei, Jin, Miao, Wang, Zhou, Wang and He.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Interleukin-13 recovers homeostasis and morphology of mitochondria. (A) Measurement of mitochondrial membrane potential using the JC-10 probe. (B) Calculation of the membrane potential change ratio with a monomer/polymer. (C) Level of ATP production. (D) mitochondria DNA (mtDNA)/nuclear DNA (nDNA) ratio. (E) Mitochondrial morphology shown by MitoTracker deep red staining. (F) Mitochondrial morphology shown by transmission electron microscope (TEM). Mitochondria was labeled with black triangle. Data are expressed as the mean ± SEM (n = 3). *P < 0.05; **P < 0.01; ***P < 0.001.