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The association of subtypes with the clinical characteristics. (A) The differences of overall survival among the three subtypes. The pairwise comparison between the three subtypes identified the differences of (B) COAD proportions with advanced stages (TNM stages III and IV), (C) proportion of samples with microsatellite instability (MSI), (D) age, (E) KRAS mutation frequency, (F) percentage of perineural invasion, and (G) percentage of lymphatic invasion.
