TABLE 2.

IC₅₀ (µM ± SD) of the benzopyrazine (1–11) against epimastigotes from T. cruzi and promastigote from L. mexicana.

Compound	L. mexicana (M378)	T. cruzi (NINOA)
1	12.46 ± 0.62	37.85 ± 0.52
2	>100	>100
3	50.86 ± 1.02	>100
4	39.83 ± 0.29	>100
5	>100	>100
6	>100	>100
7	>100	>100
8	>100	>100
9	>100	>100
10	>100	>100
11	>100	>100
Miltefosine	—	19.56 ± 0.61
Nifurtimox	9.32 ± 0.31	—