Table 1.
Characteristics of participants.
| Categorical variables | Values (%) | Continuous variables | Median (interquartile range) |
|---|---|---|---|
| Chemotherapy for breast cancer | 60 (87%) | Age at primary cancer (years) | 49 (44-55) |
| Radiotherapy for breast cancer | 47 (68%) | Age at metastasis cancer (years) | 53 (49-62) |
| Endocrine therapy for breast cancer | 25 (36%) | Disease free interval (DFI) (years) | 5 (2-8) |
| Luminal A | 7 (10%) | ||
| LuminalB | 35 (50%) | CEA (U/L) | 5.7 (2.5-44.4) |
| Her2-enhanced | 8 (12%) | CA125 (U/L) | 17.3 (10.4-47) |
| Triple-negative | 19 (28%) | CA153 (U/L) | 31.4 (16.7-53.6) |
| ER negative | 27 (39%) | WBC (10^9/L) | 6.1 (4.8-7.2) |
| ER expression 0-10% | 11 (16%) | RBC (10^9/L) | 4.02 (3.84-4.3) |
| ER expression 10-60% | 7 (10%) | HB (g/L) | 120 (110-129) |
| ER expression 60-100% | 24 (35%) | Bilirubin, total (umol/L) | 10.1 (8.7-12.3) |
| PR status | 35 (51%) | Total protein (g/L) | 67.3 (65-70.1) |
| Her2 status | 14 (20%) | ALT(U/L) | 15 (11-23) |
| Limb | 29 (42%) | ALP(U/L) | 96 (75-124) |
| Pelvis | 9 (13%) | Total bile acid (umol/L) | 3.9 (2.7-5.9) |
| Spine | 31 (45%) | AST (U/L) | 22 (18-30) |
| Bone metastasis number≥4 | 31 (45%) | LDH (U/L) | 191 (172-233) |
| Pathological fracture | 32 (46%) | Total cholesterol (mmol/L) | 4.6 (4.05-5.25) |
| Palliative surgery | 37 (54%) | Ca (mmol/L) | 2.26 (2.19-2.32) |
| Radical surgery | 32 (46%) | Mg (mmol/L) | 0.88 (0.82-0.92) |
| LN metastasis | 11 (16%) | Urea nitrogen (umol/L) | 4.7 (3.7-5.8) |
| Brain metastasis | 5 (7%) | Creatinine (umol/L) | 50 (43-55) |
| Liver metastasis | 3 (4%) | Uric acid (umol/L) | 268 (220-334) |
| Lung metastasis | 9 (13%) | Glucose (mmol/L) | 4.95 (4.49-5.25) |
| Other organ metastasis | 2 (3%) | ||
| Chemotherapy for metastasis | 44 (64%) | ||
| Radiotherapy for metastasis | 33 (48%) | ||
| Endocrine therapy for metastasis | 24 (35%) |
ER, estrogen receptor; PR, progesterone receptor; LN, lymph node; CEA, carcinoembryonic antigen; CA125, Carbohydrate antigen125; CA153, Carbohydrate antigen153; WBC, white blood cell count; RBC, red blood cell count; HB, hemoglobin; ALT, alanine aminotransferase; ALP, alkaline phosphatase; AST, Aspartate aminotransferase; LDH, lactate dehydrogenase; Ca, calcium; Mg, magnesium.