Table 3.
3-year survival risk prediction model.
| Univariable model | Multivariable (final model) | ||||
|---|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | ||
| Subtype of metastatic BC | 1.8 (1.2-2.7) | 0.002 | 1.65 (1.11-2.46) | 0.014 | |
| Multiple bone metastasis | 5.1 (1.9-13.3) | 0.001 | 2.94 (1.08-8.01) | 0.035 | |
| Pathological fracture | 2.1 (1.0-4.3) | 0.05 | – | – | |
| Organ metastasis | 4.4 (2.1-9.4) | 0.0001 | 3.75 (1.69-8.32) | 0.001 | |
| Chemotherapy | 0.54 (0.26-1.12) | 0.09 | – | – | |
| Age at primary cancer | 1 (1-1.1) | 0.06 | – | – | |
| Age at metastasis cancer | 1 (1.0-1.06) | 0.02 | – | – | |
| CEA | 1 (0.99-1.01) | 0.07 | – | – | |
| CA199 | 1 (0.99-1.01) | 0.08 | – | – | |
| CA125 | 1 (1.0-1.01) | 0.002 | – | – | |
| Hemoglobin(HB) | 0.97 (0.94-0.99) | 0.005 | – | – | |
| Bilirubin, total | 1.1 (1.01-1.15) | 0.02 | – | – | |
| ALP | 1 (1.0-1.01) | 0.005 | – | – | Included in the final model |
| LDH | 1 (1.0-1.01) | 0.0005 | 1.005 (1.001-1.009) | 0.017 | |
HR, hazard ratio; CI, confidence interval; CEA, carcinoembryonic antigen; CA125, Carbohydrate antigen125; CA153, Carbohydrate antigen153; WBC, white blood cell count; RBC, red blood cell count; HB, hemoglobin; ALT, alanine aminotransferase; ALP, alkaline phosphatase; LDH, lactate dehydrogenase; Ca, calcium; Mg, magnesium.