TABLE 1.
Summary of mitochondrial morphological effect proteins.
| Protein | Effects | References |
| Mfn1 | It is a transmembrane GTPase and mediates mitochondrial fusion. Mitochondrial fusion occurs in a variety of cell types and is an important step in the balance between fusion and fission. | Civiletto et al., 2015 |
| Mfn2 | It is a transmembrane GTPase and mediates mitochondrial fusion. Mitochondrial fusion occurs in a variety of cell types and is an important step in the balance between fusion and fission. | Civiletto et al., 2015 |
| Opa1 | It is a GTPase associated with mitochondrial fusion and apoptosis. Its formation is used to store proteins within the mitochondrial cristae to prevent proliferation. | Gomes et al., 2011 |
| L-Opa1 | The Opa1 is a dynamin-related protein associated with the inner mitochondrial membrane and functions in mitochondrial inner membrane fusion and cristae maintenance. | Gonzalez-Franquesa and Patti, 2017 |
| S-Opa1 | Inner membrane-anchored L-Opa1 undergoes proteolytic cleavage resulting in S-Opa1. | Gonzalez-Franquesa and Patti, 2017 |
| Drp1 | It mainly compresses around the break site by the mechanism of hydrolysis of GTP and then cuts off the mitochondrial membrane. | Huttemann et al., 2011 |
| Fis1 | It is involved in fragmentation fission and perinuclear clustering factors of the mitochondrial reticular organization. | Ishihara et al., 2006 |
| Mff | Promotion of cleavage-mediated Drp1 to the mitochondrial surface is associated with recruitment | Kaltenbach et al., 2007 |
| Usp30 | Deubiquitinating enzymes tethered to the OMM act as key inhibitors of autophagy by counteracting the action of parkin. | Kamerkar et al., 2018 |
| Mtp18 | Involved in mitochondrial fission through regulation of membrane fission. | Kim et al., 2011 |
| MitoPLD | It is located in the OMM and regulates mitochondrial dynamics. | Korobova et al., 2013 |
| Oma1 | Part of the quality control system of the IMM regulates the depolarization of the ΔΨm. | Koshiba et al., 2004 |
| Yme1l | Maintains mitochondrial morphology and complex respiratory activity. | Lackner, 2013 |
| Mid49 | GTPase activity in OMM proteins that control mitochondrial fission and regulate Drp1. | Leduc-Gaudet et al., 2021 |
| Mid51 | GTPase activity in OMM proteins that control mitochondrial fission and regulate Drp1. | Lee et al., 2016 |