TABLE 2.

Common diseases related to mitochondria dynamics.

Diseases	Related genes and proteins	Mitochondria impact	References
Alzheimer’s	APP, Presenilin	Fusion ↓ Fission ↑	Stanga et al., 2020
Parkinson’s	Pink1, Parkin, VPS35	Fission ↑	Tondera et al., 2009; Toda et al., 2016; Tezze et al., 2017
Charcot-Marie-Tooth disease type 2A	Mfn2	Fusion ↓	Twig et al., 2008; Touvier et al., 2015
Autosomal dominant optic atrophy	Opa1	Fusion ↓	Wai and Langer, 2016
Cardiomyocyte hypertrophy	Drp1	Fission ↑	Wang et al., 2012
Type 2 diabetes mellitus	Mfn2	Fusion ↓	Waterham et al., 2007; White et al., 2012