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. 2021 Sep 17;11:733478. doi: 10.3389/fonc.2021.733478

Table 3.

Correlation between TMB and clinicopathological parameters (p-value).

Clinical characteristics TMB threshold: 59/MB TMB threshold: 79/MB
Low group (0–59/MB) High group (>59/MB) p-value Low group (0–79/MB) High group (>79/MB) p-value
Age
≤52 2 6 1 4 4 1
>53 3 5 4 4
Liver cirrhosis
Yes 4 8 0.401 7 5 0.713
No 1 1 1 1
Tumor size
<8 cm 3 6 0.604 5 4 0.608
≥8 cm 1 5 2 4
Tumor stage
I, II stage 1 4 1 2 3 1
III, IV stage 4 7 6 5
KPS
<100 3 4 0.596 4 3 1
=100 2 7 4 5
AFP 5 11 0.002** 8 8 0.001**

TMB, tumor mutational burden; KPS, Karnofsky Performance Score; AFP, alpha fetoprotein.

**p < 0.001.