Table 1.
List of dietary-derived epigenetic modifiers classified according to their mode of action and corresponding references.
| Epigenetic regulation | Food Ingredient | Reference |
|---|---|---|
| DNMT activation/Inhibition | Selenium | Xiang et al. (59) |
| Davis et al. (60) | ||
| Biochanin A | Ito et al. (61) | |
| Quercetin | Lee et al. (62) | |
| Fang et al. (63) | ||
| Resveratrol | Kala et al. (64) | |
| Gao et al. (65) | ||
| Choline | Wolff et al. (66) | |
| Sulforaphane | Li et al. (67) | |
| Genistein | Mirza et al. (68) | |
| Nagaraju et al. (69) | ||
| Curcumin | Mirza et al. (68) | |
| Zheng et al. (70) | ||
| Luteolin | Kanwal et al. (71) | |
| Catechin | Lee et al. (62) | |
| Kanwal et al. (71) | ||
| Apigenin | Fang et al. (63) | |
| Vitamin D | Tapp et al. (72) | |
| Vitamin C | Young et al. (73) | |
| HDAC/KAT | Sulforaphane | Gao et al. (65) |
| Isothiocynanate | Beklemisheva et al. (74) | |
| Vitamin D | Fetahu et al. (75) | |
| Omega-3 FA | Patterson et al. (76) | |
| Abbas et al. (77) | ||
| Selenium | Xiang et al. (59) | |
| Caffeic acid | Bora-Tatar et al. (78) | |
| Resveratrol | Gao et al. (65) | |
| Kampferol | Berger et al. (79) | |
| HMT/HDM | Folate | Mentch & Locasale (80) |
| Vitamin C | Yin et al. (81) | |
| Omega-3 FA | Abbas et al. (77) | |
| Choline | Pogribny et al. (82) | |
| Withaferin | Mirza et al. (68) | |
| Apigenin | Kanwal et al. (71) | |
| PTM readers (MeCP2) | Genistein | Mirza et al. (68) |
| Catechin | Mirza et al. (68) | |
| Resveratrol | Mirza et al. (68) | |
| Curcumin | Mizraei et al. (83) | |
| PTM readers (BRCA) | Equol | Bosviel et al. (84) |
| MicroRNA | Vitamin D | Nunez-Lopez et al. (9) |
| Fan et al. (85) | ||
| Anthocyanin | Arola-Arnal & Blade (86) | |
| Catechin | Arola-Arnal & Blade (86) | |
| Curcumin | Mizraei et al. (83) | |
| Xin et al. (87) | ||
| Choline | Pogribny et al. (82) | |
| Sulforaphane | Gao et al. (65) | |
| Resveratrol | Xin et al. (87) | |
| Qin et al. (88) | ||
| Genistein | Zhong et al. (9) | |
| Hirata et al. (89) | ||
| Folate | Pogribny et al. (82) |
DNMT, DNA-Methyl Transferase; HDAC, Histone De-acetylase; KAT, Lysine Acetyl Transferase; HMT, Histone Methyl Transferase; HDM, Histone De-Methylase; PTM, Post-Translational Modification; MeCP2, Methyl CpG Binding Protein 2; BRCA, BRCA1 DNA Repair-Associated protein; miR, microRNA.