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. 2021 Sep 17;12:752359. doi: 10.3389/fimmu.2021.752359

Table 1.

List of dietary-derived epigenetic modifiers classified according to their mode of action and corresponding references.

Epigenetic regulation Food Ingredient Reference
DNMT activation/Inhibition Selenium Xiang et al. (59)
Davis et al. (60)
Biochanin A Ito et al. (61)
Quercetin Lee et al. (62)
Fang et al. (63)
Resveratrol Kala et al. (64)
Gao et al. (65)
Choline Wolff et al. (66)
Sulforaphane Li et al. (67)
Genistein Mirza et al. (68)
Nagaraju et al. (69)
Curcumin Mirza et al. (68)
Zheng et al. (70)
Luteolin Kanwal et al. (71)
Catechin Lee et al. (62)
Kanwal et al. (71)
Apigenin Fang et al. (63)
Vitamin D Tapp et al. (72)
Vitamin C Young et al. (73)
HDAC/KAT Sulforaphane Gao et al. (65)
Isothiocynanate Beklemisheva et al. (74)
Vitamin D Fetahu et al. (75)
Omega-3 FA Patterson et al. (76)
Abbas et al. (77)
Selenium Xiang et al. (59)
Caffeic acid Bora-Tatar et al. (78)
Resveratrol Gao et al. (65)
Kampferol Berger et al. (79)
HMT/HDM Folate Mentch & Locasale (80)
Vitamin C Yin et al. (81)
Omega-3 FA Abbas et al. (77)
Choline Pogribny et al. (82)
Withaferin Mirza et al. (68)
Apigenin Kanwal et al. (71)
PTM readers (MeCP2) Genistein Mirza et al. (68)
Catechin Mirza et al. (68)
Resveratrol Mirza et al. (68)
Curcumin Mizraei et al. (83)
PTM readers (BRCA) Equol Bosviel et al. (84)
MicroRNA Vitamin D Nunez-Lopez et al. (9)
Fan et al. (85)
Anthocyanin Arola-Arnal & Blade (86)
Catechin Arola-Arnal & Blade (86)
Curcumin Mizraei et al. (83)
Xin et al. (87)
Choline Pogribny et al. (82)
Sulforaphane Gao et al. (65)
Resveratrol Xin et al. (87)
Qin et al. (88)
Genistein Zhong et al. (9)
Hirata et al. (89)
Folate Pogribny et al. (82)

DNMT, DNA-Methyl Transferase; HDAC, Histone De-acetylase; KAT, Lysine Acetyl Transferase; HMT, Histone Methyl Transferase; HDM, Histone De-Methylase; PTM, Post-Translational Modification; MeCP2, Methyl CpG Binding Protein 2; BRCA, BRCA1 DNA Repair-Associated protein; miR, microRNA.