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. 2021 Sep 17;12:715701. doi: 10.3389/fmicb.2021.715701

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Copyright © 2021 Kuleš, Rubić, Beer Ljubić, Bilić, Barić Rafaj, Brkljačić, Burchmore, Eckersall and Mrljak.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of the urinary metabolites identified by the targeted metabolomics approach in non-azotemic dogs with babesiosis and normal urine protein to creatinine ratio (UPC < 0.5) (group A), non-azotemic dogs with babesiosis and UPC > 0.5 (group B), azotemic dogs with babesiosis and UPC > 1 (group C), and healthy dogs (control group). All metabolites shown demonstrated a statistically significant difference between groups by ANOVA (p < 0.05). Data are presented as box and whiskers plot (mean ± SD).