Table 4.
Comparison of the median values from heparin dose and coagulation assays in the group of patients with and without bleeding complications.
| Bleeding | No bleeding | p-value | |
|---|---|---|---|
| complicationsa | complicationsa | ||
| Heparin dose (IU/kg/h) | 26.3 (0–44) | 20.6 (0–161.3) | 0.03 |
| ACT (s) | 185 (141–999) | 182 (118–999) | 0.90 |
| aPTT (s) | 69.4 (35.1–151) | 59.8 (28.7–151) | 0.01 |
| Anti-factor Xa (IU/ml) | 0.28 (0.09–0.75) | 0.27 (0.09–1.9) | 0.42 |
| CT-INTEM (s) | 297 (204–1235) | 279 (154–5126) | 0.15 |
| CT-Diff (s) | 61 (−46 to 960) | 58 (−148 to 4785) | 0.6 |
ACT, activated clotting time; aPTT, activated partial thromboplastin time; CT-INTEM, clotting time in INTEM; CT-Diff, clotting time in INTEM minus clotting time in HEPTEM.
a
Median values and interquartile ranges.
The bold values symbolize that the value is statistically significant.