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. 2021 Sep 17;13:734992. doi: 10.3389/fnagi.2021.734992

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Copyright © 2021 Alisch, Kiely, Triebswetter, Alsameen, Gong, Khattar, Egan and Bouhrara.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Regressions of relaxometry measures (T₁ and T₂), DTI measures (FA and MD), or CBF with age. For each plot, the coefficient of determination, R², and p-value, p, are reported. T₁, T₂ and MD exhibit non-linearly increasing trends with age while FA and CBF exhibit a non-linearly decreasing trends with age.