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. 2021 Oct 1;14:238. doi: 10.1186/s12920-021-01056-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Comparison of polygenic risk score report visuals. Polygenic risk scores were compared based on numeric estimates reported, risk descriptions, and supporting visuals to convey risk.

Written copyright permission was obtained from 3/7 groups to reproduce figures from company websites and provided through personal communication in this manuscript. References for sample polygenic score reports shown here: Scripps MyGeneRank [29], Color Health [32], Impute.me [34]. Copyright permissions were not obtained for the remaining report visuals discussed in the manuscript; sample reports are referenced within the manuscript: Myriad Genetics [27], Gene Plaza [33], 23andMe [36], Ambry Genetics [22–24]. Since this review, Ambry Genetics [22–24] removed the ‘AmbryScore’ polygenic score product from the market in May 2021 [e-mail communication]