Table 5.

Change in anxious symptom severity (7-item Generalized Anxiety Disorder scale) over time.

Time point	Estimated marginal, mean (SE)	Modeled change from baseline, mean (95% CIa)	P valueb
Baseline	8.67 (0.18)	N/Ac	N/A
Week 2	8.56 (0.20)	−0.11 (−0.51 to 0.29)	.58
Week 4	8.26 (0.21)	−0.41 (−0.83 to 0.01)	.06
Week 6	7.86 (0.22)	−0.81 (−1.27 to −0.36)	<.001
Week 8	7.63 (0.24)	−1.04 (−1.54 to −0.55)	<.001
Week 10	7.33 (0.25)	−1.34 (−1.85 to −0.83)	<.001
Week 12	7.27 (0.25)	−1.40 (−1.92 to −0.88)	<.001
Week 14	7.18 (0.27)	−1.49 (−2.05 to −0.93)	<.001
Week 16	7.48 (0.30)	−1.20 (−1.81 to −0.58)	<.001
Week 18	7.22 (0.30)	−1.45 (−2.07 to −0.83)	<.001

^aThe 95% CI refers to the change from baseline.

^bP values indicate the significance level for comparisons between baseline scores and scores at each of the follow-up assessments.

^cN/A: not applicable.