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. 2021 Jan 15;6(3):344–351. doi: 10.1136/svn-2020-000490

Figure 6.

Figure 6

Wip1 deficiency increased neuroinflammation through the NF-κB signalling pathway after ischaemia/reperfusion. (A) Left: representative western blot images of the expression of NF-κB and p-NF-κB. Right: quantification of the expression of NF-κB and p-NF-κB by western blot analysis. n=3 mice/group. Data are expressed as mean±SEM; *p<0.05 (WT MCAO group vs Wip1-KO MCAO group), **p<0.01 (Wip1-KO MCAO group vs Wip1-KO MCAO+lentivirus-Ppm1d group). KO, knockout; MCAO, middle cerebral artery occlusion; NF-κB, nuclear factor kappa B; Wip1, wild-type p53-induced protein phosphatase 1.