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. 2021 May 25;32(6):1067–1077. doi: 10.1021/acs.bioconjchem.1c00123

Table 3. HIV inhibition by Peptide-Porphyrin Conjugates.

  IC50 (μM)
Conjugates MP-P3 MP-P5 P4-MP MP-L-P3 P4-L-MP
100 TCDI50 16.12 ± 1.3 33.1 ± 1.38 34.03 ± 1.25 16.59 ± 1.29 26.35 ± 1.24
10 TCDI50a 1.38 ± 1.1 10 ± 2.9 5.77 ± 1.17 1.985 ± 1.27 10.69 ± 1.33
Control MP PP
100 TCDI50 >50 >50
a

Approximate physiological conditions presented in a HIV brain infection.