Table 3. HIV inhibition by Peptide-Porphyrin Conjugates.
IC50 (μM) | |||||
---|---|---|---|---|---|
Conjugates | MP-P3 | MP-P5 | P4-MP | MP-L-P3 | P4-L-MP |
100 TCDI50 | 16.12 ± 1.3 | 33.1 ± 1.38 | 34.03 ± 1.25 | 16.59 ± 1.29 | 26.35 ± 1.24 |
10 TCDI50a | 1.38 ± 1.1 | 10 ± 2.9 | 5.77 ± 1.17 | 1.985 ± 1.27 | 10.69 ± 1.33 |
Control | MP | PP | ||
---|---|---|---|---|
100 TCDI50 | >50 | >50 |
Approximate physiological conditions presented in a HIV brain infection.