Table 1.
Characteristics and laboratory results of patients with BTI and healthy subjects
| Overall n = 86 | BTI n = 51 | Control n = 35 | P value† | |
|---|---|---|---|---|
| Age, mean ± SD (years) | 48.5 ± 15.08 | 50.9 ± 16.63 | 44.9 ± 11.83 | 0.117 |
| Gender, male/female | 43/43 | 27/24 | 16/19 | 0.510 |
| Laboratory tests | ||||
| I‐FABP (ng/mL) | <0.001* | |||
| Mean ± SD | 2.8 ± 1.91 | 3.8 ± 1.77 | 1.4 ± 0.99 | |
| Median (IQR) | 2.4 (37.0–60.0) | 3.8 (2.4–5.0) | 1.1 (0.7–1.9) | |
| WBCs (×103/μL) | <0.001* | |||
| Mean ± SD | 8.2 ± 4.00 | 9.6 ± 4.14 | 5.4 ± 1.24 | |
| Median (IQR) | 7.0 (5.4–10.1) | 8.7 (6.8–10.8) | 5.1 (4.3–6.3) | |
| hs‐CRP (mg/dL) | <0.001* | |||
| Mean ± SD | 17.2 ± 45.81 | 22.0 ± 51.24 | 1.0 ± 1.44 | |
| Median (IQR) | 2.4 (0.8–10.2) | 3.5 (1.2–16.8) | 0.4 (0.2–0.9) | |
| Total bilirubin (μmol/L) | 0.032* | |||
| Mean ± SD | 31.1 ± 45.82 | 36.2 ± 50.62 | 12.7 ± 3.84 | |
| Median (IQR) | 15.4 (10.9–25.5) | 17.6 (10.9–30.4) | 12.0 (10.2–14.5) | |
| Zonulin (ng/mL) | 0.274 | |||
| Mean ± SD | 9.9 ± 12.96 | 9.5 ± 14.22 | 10.5 ± 11.08 | |
| Median (IQR) | 5.9 (1.5–17.9) | 3.6 (0.3–22.1) | 11.0 (3.3–14.8) | |
| Hemoglobin (g/L) | 0.854 | |||
| Mean ± SD | 134.5 ± 23.31 | 134.5 ± 24.06 | 134.1 ± 21.15 | |
| Median (IQR) | 139.0 (125.0–147.0) | 139.0 (125.0–146.0) | 133.5 (125.0–149.0) | |
| Platelets (×103/μL) | 0.570 | |||
| Mean ± SD | 236.9 ± 58.86 | 234.7 ± 61.89 | 244.9 ± 47.31 | |
| Median (IQR) | 239.0 (201.0–269.0) | 240.0 (192.0–272.0) | 238.0 (222.0–261.0) | |
*
Significant difference.
†
To compare differences between the BTI and control groups, two‐sample t‐test or Wilcoxon signed‐rank test was applied for continual variables; Chi‐square test was applied for categorical variables.
BTI, biliary tract infection; hs‐CRP, high‐sensitivity C‐reactive protein; I‐FABP, intestinal fatty acid‐binding protein; IQR, interquartile range; WBC, white blood cells.