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. 2021 Aug 20;5(10):1160–1165. doi: 10.1002/jgh3.12644

Table 2.

Sensitivity and specificity of I‐FABP, hs‐CRP, and zonulin for diagnosis of BTI

Index AUCROC Cutoff Sensitivity Specificity 95% CI PPV NPV
I‐FABP 0.884 2.1 0.804 0.829 0.814–0.954 0.872 0.744
hs‐CRP 0.880 1.0 0.863 0.800 0.785–0.976 0.963 0.632
Zonulin 0.570 6.9 0.660 0.657 0.444–0.697 0.733 0.575

AUCROC, area under ROC curves; BTI, biliary tract infection; CI, confidence interval; hs‐CRP, high‐sensitivity C‐reactive protein; I‐FABP, intestinal fatty acid‐binding protein; NPV, negative predictive value; PPV, positive predictive value; ROC, receiver operating characteristic.