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. 2021 Oct 1;21:246. doi: 10.1186/s12906-021-03423-x

Table 2.

Anti-influenza A virus effects of some medicinal plants extracts and fractions

Plant Extracts or Fractions Concentration in DMSO CC50 (μg/ml) NCTC (μg/ml) & EC50 (μg/ml) Selectivity index
(SI = CC50/EC50)
Glycyrrhiza glabra Crude E. 100 mg/ml 881.87 ± 0.03 55.12 16
Glycyrrhiza glabra Chloroform F. 100 mg/ml 5.19 ± 0.00 2.57 2
Glycyrrhiza glabra Methanol F. 100 mg/ml 3529.48 ± 0.76 441.12 8
Myrtus communis Crude E. 100 mg/ml 10.40 ± 0.00 2.60 4
Myrtus communis Chloroform F. 100 mg/ml 2.60 ± 0.00 0.65 4
Myrtus communis Methanol F. 100 mg/ml 603.67 ± 0.60 37.73 16
Melissa officinalis Crude E. 100 mg/ml 1813.99 ± 0.23 113.37 16
Melissa officinalis Chloroform F. 100 mg/ml 1427.10 ± 0.45 44.62 32
Melissa officinalis Methanol F. 100 mg/ml 4413.80 ± 3.69 551.72 8
Hypericum perforatum Crude E. 100 mg/ml 10.41 ± 0.00 1.30 8
Hypericum perforatum Chloroform F. 100 mg/ml 10.99 ± 0.00 2.75 4
Hypericum perforatum Methanol F. 100 mg/ml 3929.08 ± 2.47 122.7 32
Tilia platyphyllos Crude E. 100 mg/ml 152.26 ± 0.50 9.56 15.92
Tilia platyphyllos Chloroform F. 100 mg/ml 267.45 ± 8.8 16.69 16.03
Tilia platyphyllos Methanol F. 100 mg/ml 277.56 ± 3.19 34.62 8.02
Salix alba Crude E. 100 mg/ml 3647.45 ± 52.52 113.70 32
Salix alba Chloroform F. 100 mg/ml 1755.28 ± 0.89 219.37 8
Salix alba Methanol F. 100 mg/ml 2816.86 ± 77.80 88.03 32
Camellia sinensis Crude E. 100 mg/ml 161.89 ± 2.30 20.25 8
Camellia sinensis Chloroform F. 100 mg/ml 13.28 ± 0.00 1.62 8.17
Camellia sinensis Methanol F. 100 mg/ml 877.28 ± 3.80 27.41 32
Camellia sinensis)fermented( Crude E. 100 mg/ml 1038.192 ± 88.73 129.87 8
Camellia sinensis)fermented( Chloroform F. 100 mg/ml 875.61 ± 7.55 109.50 8
Camellia sinensis)fermented( Methanol F. 100 mg/ml 405.13 ± 3.71 50.62 8
Amantadine hydrochloride 2000 μg/ml H2O 197.001 ± 1.533 98.500 2
Oseltamivir carboxylate 4000 μg/ml H2O 788.505 ± 6.006 394.250 2

CC50 50% cytotoxic concentration, EC50 50% effective concentration, NCTC non-cytotoxic concentrations (EC50 and NCTC values were equal), SI Selectivity Index