Table 2.

Adverse Events

Adverse Event	Grade	Experimental Arm (N = 83)		Standard Arm (N = 40)
Alopecia	All grades	37	(45%)	19	(48%)
	Grade 3-4	0	(0%)	0	(0%)
Anemia	All grades	6	(7%)	0	(0%)
	Grade 3-4	1	(1%)	0	(0%)
Anorexia	All grades	25	(30%)	10	(25%)
	Grade 3-4	1	(1%)	0	(0%)
Blurred vision	All grades	16	(19%)	3	(8%)
	Grade 3-4	1	(1%)	0	(0%)
Chills	All grades	3	(4%)	1	(3%)
	Grade 3-4	0	(0%)	0	(0%)
Constipation	All grades	30	(36%)	15	(38%)
	Grade 3-4	0	(0%)	0	(0%)
Dehydration	All grades	9	(11%)	2	(5%)
	Grade 3-4	0	(0%)	0	(0%)
Dermatitis radiation	All grades	17	(20%)	8	(20%)
	Grade 3-4	0	(0%)	0	(0%)
Diarrhea	All grades	16	(19%)	5	(13%)
	Grade 3-4	0	(0%)	2	(5%)
Dizziness	All grades	15	(18%)	6	(15%)
	Grade 3-4	0	(0%)	0	(0%)
Dry mouth	All grades	12	(14%)	7	(18%)
	Grade 3-4	0	(0%)	0	(0%)
Dysgeusia	All grades	15	(18%)	7	(18%)
	Grade 3-4	0	(0%)	0	(0%)
Dyspepsia	All grades	10	(12%)	2	(5%)
	Grade 3-4	1	(1%)	0	(0%)
Ear pain	All grades	6	(7%)	1	(3%)
	Grade 3-4	0	(0%)	0	(0%)
Edema limbs	All grades	14	(17%)	4	(10%)
	Grade 3-4	0	(0%)	1	(3%)
Fatigue	All grades	67	(81%)	29	(73%)
	Grade 3-4	6	(7%)	1	(3%)
Headache	All grades	57	(69%)	20	(50%)
	Grade 3-4	3	(4%)	1	(3%)
Insomnia	All grades	31	(37%)	7	(18%)
	Grade 3-4	0	(0%)	0	(0%)
Mucosal infection	All grades	8	(10%)	3	(8%)
	Grade 3-4	0	(0%)	0	(0%)
Nausea	All grades	45	(54%)	17	(43%)
	Grade 3-4	0	(0%)	0	(0%)
Vomiting	All grades	12	(14%)	5	(13%)
	Grade 3-4	0	(0%)	0	(0%)
Weight loss	All grades	10	(12%)	3	(8%)
	Grade 3-4	0	(0%)	0	(0%)