Fig. 1.
Epidemiology of pediatric low-grade gliomas. (A) Average annual age-adjusted incidence rates with 95% confidence intervals for individuals aged 19 years or younger with pilocytic astrocytoma (PA; red) vs diffuse astrocytoma (DA; blue) by age at initial diagnosis. Rates are per 100 000 and age-adjusted to the 2000 US Standard Population (19 age groups—Census P25-1130) standard; confidence intervals (Tiwari mod) are 95% for rates. CBTRUS: data provided by CDC’s National Program of Cancer Registries and NCI’s Surveillance, Epidemiology and End Results Program, 2000-2017. (B) Kaplan-Meier overall survival curve for PA (red) vs DA (blue) in individuals aged 19 years or younger (log-rank P value). National Program of Cancer Registries, 2001-2016.