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ICAT may inhibit Wnt signaling pathway by binding to β-catenin in CRC. (A) Co-IP and immunofluorescence detection of ICAT and β-catenin binding in stable overexpression SW480 cells. (B) Co-IP and immunofluorescence detection of ICAT and β-catenin binding in stable overexpression DLD1 cells.
Abbreviations: ICAT, inhibitor of β-catenin and T-cell factor; CRC, colorectal cancer; co-IP, co-immunoprecipitation.
