FIG. 1.

Brain MRI at the age of 2.5 (panels A‐C) and 8 (panels D‐F) years. Representative images, including axial views at the levels of basal ganglia/thalami (panels A & D) and cerebellum (panels B & E), and coronal views (panels C & F), were shown. Delayed myelination was evident on T2‐weighted imaging at 2.5 years of age, as reflected by the diffusely increased signal intensities in cerebral white matter (panels A & C). Myelination has improved significantly at 8 years of age, with only faintly increased signals in peripheral white matter (panels D & F).