TABLE 3.
Predictors of MoCA change
| Variable | Univariate model | Multivariate model | ||||||
|---|---|---|---|---|---|---|---|---|
| t | β | SE | P | t | β | SE | P | |
| Age | −3.14 | −0.06 | 0.02 | 0.002 | −3.19 | −0.07 | 0.02 | 0.002 |
| Male sex | 1.77 | 0.75 | 0.42 | 0.079 | 1.32 | 0.54 | 0.41 | 0.19 |
| Education | 0.87 | 0.06 | 0.07 | 0.39 | 1.25 | 0.09 | 0.07 | 0.21 |
| Disease duration | 0.65 | 0.09 | 0.14 | 0.52 | 0.51 | 0.07 | 0.13 | 0.61 |
| MDS‐UPDRS III | −0.06 | −0.001 | 0.03 | 0.95 | 1.01 | 0.03 | 0.03 | 0.31 |
| Aggressive dreams | −3.02 | −1.35 | 0.45 | 0.003 | −3.34 | −1.49 | 0.45 | 0.001 |
| Vivid dreams | −1.35 | −0.55 | 0.41 | 0.18 | – | – | – | – |
| DEBs | −2.62 | −1.04 | 0.40 | 0.009 | – | – | – | – |
| GDS‐15 | −1.88 | −0.17 | 0.09 | 0.06 | – | – | – | – |
| STAI | −2.13 | −0.03 | 0.01 | 0.03 | ‐ | ‐ | ‐ | ‐ |
| ESS | −1.03 | −0.07 | 0.06 | 0.30 | – | – | – | – |
| SCOPA‐AUT | −4.40 | −0.13 | 0.03 | <0.001 | – | – | – | – |
Values in bold denote significant predictors of MoCA change in univariate and adjusted multivariate models in the primary analysis.
Abbreviations: MoCA, Montreal Cognitive Assessment; SE, standard error; MDS‐UPDRS III, Movement Disorder Society–Unified Parkinson's Disease Rating Scale Part III; DEBs, dream enactment behaviors; GDS‐15, Geriatric Depression Scale 15‐item; STAI, Spielberger's State–Trait Anxiety Inventory; ESS, Epworth Sleepiness Scale; SCOPA‐AUT, Scales for Outcomes in Parkinson's Disease–Autonomic.