Table 2.
Summary of meta-analysis on the reduction of urinary cortisol pre- and post-intervention.
SMD | 95% CI | I² | P | PI | Included studies (n) | Included patients (n) | |
---|---|---|---|---|---|---|---|
Pasireotidea | -0.94 | -1.17, -0.71 | 51.9% | 0.358 | -1.60, -0.28 | 7 | 503 |
Randomized studies only | -0.94 | -1.14, -0.74 | 7% | 0.028 | -1.44, -0.45 | 2 | 312 |
Cabergoline | -2.4 | -4.5, -0.25 | 95% | – | – | 4 | 68 |
Ketoconazole | -2.88 | -5.18, -0.58 | 96.6% | – | – | 4 | 246 |
I2, Higgins test of heterogeneity; CI, confidence interval; PI, predictive interval; SMD, standard mean deviation.
Randomized and prospective studies.