Table 2.

IC₅₀ (pIC₅₀±SEM, n=3) values of indicated compounds against a panel of human PARPs.

	1 (OUL35)[a]	10	20
PARP1	>100 μm	>100 μm	>100 μm
PARP2	>100 μm	27 μm	1.7 μm (5.77±0.12)
PARP3	>100 μm	>100 μm	>100 μm
PARP4	23 μm	>100 μm	7 μm
TNKS1	>100 μm	>100 μm	21 μm
TNKS2	>100 μm	>100 μm	6.5 μm
PARP10	330 nm	3.64 μm (5.44±0.03)	480 nm (6.32±0.15)
PARP12 [b]	>100 μm	>10 μm	>10 μm
PARP14	23 μm	>100 μm	41 μm
PARP15 [b]	>10 μm	11 μm (4.95±0.10)	1.7 μm (5.56±0.11)
PARP16 [b]	4.17 μm	>10 μm	>10 μm

[a] Data taken from Venkannagary et al. Cell Chem. Biol. (2016). [b] Concentration limited by DMSO tolerance.