TABLE 1.
Baseline participant characteristics at screening
| Participant characteristics | |
| Sex, female/male | 4/10 |
| Age, years | 72.9 ± 4.0 |
| Height, cm | 170 ± 6 |
| Weight, kg | 72.9 ± 7.1 |
| BMI, kg/m2 | 25.2 ± 2.3 |
| Systolic blood pressure, mmHg | 144 ± 12 |
| Diastolic blood pressure, mmHg | 84 ± 6 |
| Heart rate, beats per minute | 63 ± 10 |
| 6-minute walking distance, m | 393 ± 53 |
| Maximal aerobic capacity, L/min | 2.31 ± 0.66 |
| Maximal cycling resistance, Watt | 176 ± 63 |
| Blood parameters | |
| Hemoglobin, mmol/L | 9.1 ± 0.6 |
| Creatinine, μmol/L | 88 ± 18 |
| eGFR CKD-EPI | 71.6 ± 10.1 |
| Alkaline phosphatase, U/L | 74 ± 22 |
| γGT, U/L | 23 ± 9 |
| AST, U/L | 23 ± 5 |
| ALT, U/L | 21 ± 5 |
| Bilirubin, μmol/L | 11.5 ± 5.0 |
| Cholesterol, mmol/L | 5.1 ± 0.7 |
| HDL cholesterol, mmol/L | 1.7 ± 0.5 |
| LDL cholesterol, mmol/L | 2.9 ± 0.6 |
| Triglycerides, mmol/L | 1.03 ± 0.32 |
| Free fatty acids, mmol/L | 0.47 ± 0.11 |
| Hb1Ac, % | 5.4 ± 0.3 |
| Glucose, mmol/L | 5.1 ± 0.6 |
| Baecke Physical Activity Index | 7.26 ± 1.34 |
| Work Index | 1.62 ± 0.98 |
| Sport Index | 2.25 ± 0.49 |
| Leisure Index | 3.39 ± 0.41 |
| Medication used, n | |
| Statin | 1 |
| Proton pump inhibitor | 1 |
| Thrombocyte aggregation inhibitor | 1 |
| Calcium and vitamin D | 2 |
| Thyromimetic | 1 |
| Anti-hypertensive drugs | 3 |
| Alpha blocker | 1 |
| NSAID | 1 |
| Benzodiazepine | 1 |
Data are presented as means ±SDs, n = 14. Abbreviations: ALT, alanine transaminase; AST, aspartate transaminase; eGRF CKD-EPI, estimated glomerular filtration rate chronic kidney disease epidemiology collaboration; Hb1Ac, glycated hemoglobin; NSAID, nonsteroidal anti-inflammatory drug; γGT, gamma-glutamyltransferase.