Kalanin 2005.

Methods	Multicentre, randomised, double‐blind, placebo‐controlled study
Participants	82 male and 86 female outpatients from 1 to 15 years of age with recurrent AOM. Mean age was 6.14 years. The population is from Prague and Mid‐Bohemia region, Czech Republic
Interventions	Intervention: 3 daily doses of nasal wash, each consisting of 2 squirts per nostril, at regular assigned times daily (after waking up; after lunch; before going to bed). Patients received one of the following treatments as predetermined by their randomisation number: a solution of nasal xylitol (11% pure xylitol; XLEAR®) or distilled water
Outcomes	AOM recurrence; frequency of antibiotic therapy; frequency of upper airways infections; adverse events
Notes	Xlear Inc. has been contacted for further information about this unpublished report

AOM: acute otitis media