Table 3.

Top 10 risk factors ranked by mean absolute Shapley value for cohorts A, B, C, and D (full model).

Risk factor			ShapVal		P value
Cohort A
	Age	0.442		.002
	Treatments taken count	0.093		.002
	Cystatin C	0.088		.002
	Waist-to-hip ratio	0.085		.002
	Townsend deprivation index	0.059		.004
	HbA1ca	0.056		.002
	Pulse rate	0.048		.002
	Hypertension	0.048		.002
	Apolipoprotein A	0.027		.016
	HDLb cholesterol	0.026		.016
Cohort B
	Age	0.708		.002
	Testosterone	0.069		.002
	Treatments taken count	0.048		.002
	Waist circumference	0.035		.002
	RBCc distribution width	0.027		.002
	Cystatin C	0.024		.002
	Townsend deprivation index	0.023		.002
	Pulse rate	0.019		.004
	Systolic blood pressure	0.016		.002
	Lymphocyte percentage	0.015		.004
Cohort C
	Waist-to-hip ratio	0.113		.002
	Townsend deprivation index	0.096		.002
	Age	0.088		.002
	Treatments taken count	0.063		.002
	Waist circumference	0.044		.002
	Self-report: noncancer count	0.043		.002
	Hypertension	0.036		.002
	Cystatin C	0.030		.024
	T2DM	0.030		.002
	Apolipoprotein A	0.024		.052
Cohort D
	Age	0.519		.002
	Townsend deprivation index	0.136		.002
	Waist-to-hip ratio	0.131		.002
	Treatments taken count	0.115		.002
	Waist circumference	0.110		.002
	Cystatin C	0.096		.002
	Testosterone	0.086		.002
	Hypertension	0.061		.002
	RBC distribution width	0.046		.002
	Pulse rate	0.036		.006

^aHbA1c: hemoglobin A1c.

^bHDL: high-density lipoprotein.

^cRBC: red blood cell.

^dT2DM: type 2 diabetes mellitus.