Table 1:
Characteristics of study participants by PM2.5 quintile
| Characteristic | Quintile 1 | Quintile 2 | Quintile 3 | Quintile 4 | Quintile 5 |
|---|---|---|---|---|---|
| Number of patients | 1858 | 1857 | 1857 | 1857 | 1857 |
| PM2.5 (μg/m3) | 5.3 ± 1.9 | 8.7 ± 0.4 | 9.7 ± 0.3 | 10.8 ± 0.3 | 12.8 ± 1.1 |
| Age, years | 68.1 ± 9.6 | 68.2 ± 9.3 | 67 ± 9.6 | 68 ± 9.3 | 68 ± 9.1 |
| Female, n (%) | 601 (32%) | 637 (34%) | 630 (34%) | 719 (39%) | 717 (39%) |
| Black Race, n (%) | 348 (19%) | 434 (23%) | 657 (35%) | 686 (37%) | 797 (43%) |
| Current Smoker, n (%) | 219 (12%) | 225 (12%) | 257 (14%) | 244 (13%) | 285 (15%) |
| History of clinical CVD, n (%) | 389 (21%) | 302 (16%) | 283 (15%) | 300 (16%) | 277 (15%) |
| History of subclinical CVD, n (%) | 118 (6.4%) | 72 (3.9%) | 92 (5.0%) | 89 (4.8%) | 113 (6.1%) |
| Statin, n (%) | 884 (48%) | 827 (45%) | 793 (43%) | 762 (41%) | 767 (42%) |
| Aspirin, n (%) | 933 (50%) | 980 (53%) | 935 (51%) | 940 (51%) | 945 (51%) |
| Assigned to Intensive lowering strategy | 931 (50%) | 946 (51%) | 915 (49%) | 916 (49%) | 927 (50%) |
| Chronic Kidney Disease, n (%) | 504 (27%) | 613 (33%) | 474 (26%) | 543 (29%) | 497 (27%) |
| eGFR, ml/min/1.73 m2 | 73 ± 21 | 69 ± 20 | 73 ± 21 | 71 ± 20 | 72 ± 20 |
| Framingham 10-year risk | 20.4 ± 11.2 | 20.8 ± 11.0 | 20.4 ± 11.2 | 19.6 ± 10.4 | 19.2 ± 10.2 |
| Body Mass Index | 29.4 ± 5.4 | 29.7 ± 5.7 | 30.1 ± 5.9 | 29.9 ± 5.8 | 30.2 ± 6.0 |
| Baseline Blood Pressure (mm Hg) | |||||
| Systolic | 139 ± 15 | 141 ± 16 | 140 ± 15 | 139 ± 16 | 139 ± 16 |
| Diastolic | 77 ± 12 | 79 ± 12 | 79 ± 12 | 78 ± 12 | 79 ± 12 |
| Number of antihypertensives | 1.8 ± 1.0 | 1.8 ± 1.1 | 1.9 ± 1.1 | 1.9 ± 1.0 | 1.9 ± 1.0 |
| Not on antihypertensives | 150 (8.1%) | 198 (11%) | 196 (11%) | 171 (9%) | 158 (9%) |
| Fasting Laboratory (mg/dL) | |||||
| Total cholesterol | 187 ± 41 | 190 ± 42 | 192 ± 41 | 191 ± 41 | 190 ± 41 |
| HDL cholesterol | 52 ± 14 | 53 ± 15 | 53 ± 15 | 54 ± 14 | 54 ± 15 |
| Triglycerides | 132 ± 93 | 128 ± 88 | 126 ± 80 | 123 ± 87 | 120 ± 103 |
| Glucose | 98 ± 12 | 100 ± 14 | 99 ± 13 | 98 ± 14 | 99 ± 14 |