Figure 5.
Effect of SDHC overexpression on fiber type identity in IL13TG mice skeletal muscles. Preelectroporation and postelectroporation EDL muscles from IL13TG mice were immunostained with antibodies to detect MyHC isoforms to characterize fiber types. After electroporation, there was an increase in relatively more oxidative type 2A and 2X fibers and a reduction in relatively glycolytic type 2B fibers without a significant change in the number of type I fibers. Scale bars, 100 μm. N = 4. *P < 0.05.