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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Nucl Med Biol. 2021 Apr 21;98-99:8–17. doi: 10.1016/j.nucmedbio.2021.04.001

Fig. 5.

Fig. 5

Biodistribution (a) and PET/CT images (b) in C57BL/6 mice with bilateral s.c. mT4 tumors at 48 h after the first (upper row) and second round of injections (bottom row) with [64Cu]Cu-NOTA-aCD40 (control), [64Cu]Cu-NOTA-aCD40 and aCD40 mAb without (monotherapy, MT) or with aPD-1 and aCTLA-4 mAbs (combination therapy, CT). L with thick arrowhead and S with narrow arrowheads represent liver and spleen, respectively. Asterisks are **** (P < 0.0001), **(P < 0.01), and *(P < 0.05).