Table 3.
Pre- and post-operative quality of life improvement after giant hiatus hernia surgery, using a variety of questionnaires
| Authors | Total number of patients (number of patients followed up) | Length of follow-up (months) | Pre-operative score | Post-operative score | Improvement in QoL (P) | Additional follow-up |
|---|---|---|---|---|---|---|
|
| ||||||
| GERD-HRQL | ||||||
| Stringham et al., 2017 | 106 | 12 | 22.5 | 3 | P<0.001 | Score 7 (P<0.001*) |
| Asti et al., 2016 | 84 (84) | 24 | 15.5 (MU), 18 (NM) | 1 (MU), 3 (NM) | P<0.001 for both | n/a |
| Shreshtha et al., 2019 | 60 (60) | 60 | 27 (Veritas), 27 (Strattice) | 0 (Veritas), 0 (Strattice) | P<0.005 | n/a |
| Zahiri et al., 2017 | 317 | 12 | 20.9 (initial), 21.1 (re-do) | 6.5 (initial), 8 (re-do) | P=0.175 | n/a |
| Zehetner et al., 2009 | 35 (21) | 14 | n/a | 5 | 91.3% satisfied, 4.3% neutral, 4.3% dissatisfied | n/a |
| Parameswaran et al., 2006 | 49 (31) | 19 | 18 | 1 | P<0.001 | n/a |
| Louie et al., 2011 | 58 (55) | 15 | 14.7 | 7.6 | P<0.001 | P<0.001* |
| Merzilikin et al., 2017 | 137 (59) | 60 | 11 | 5 | P=0.03 | n/a |
| Hall et al., 2018 | 314 (188) | 24 | 14.4 | 6.6 | P<0.0001 | At 1 year - 5.7 (P<0.0001) At 2 years - 5.8 (P<0.0001) |
| Marano et al., 2014 | 13 | 12 | 37.4 | 3.2 | P<0.0001 | n/a |
| Siboni et al., 2019 | 49 (37) | 24 | 11 | 2 | P<0.001 | n/a |
| Qureshi et al., 2013 | 21 (14) | 13 | 22.9 | 6.9 | P<0.03 | n/a |
| Ilyashenko et al., 2018 | 98 (69) | 48 | 17.5 (MU, n=50); 16.3 (NM, n=48) | 3.8 (MU, n=34); 5.9 (NM, n=35) | P<0.0001 for both | n/a |
| Whitson et al., 2006 | 61 (52) | 24 | n/a | 1.15 | Excellent 96.2%, Good 1.9% | n/a |
| Karmali et al., 2008 | 93 (71) | 17 (LS) 21 (OS) |
n/a | n/a | Excellent result in 89% (LS) and 77% (OS) | n/a |
| Pierre et al., 2002 | 203 | 18 | n/a | 2.4 | 84% Excellent, 8% good, 7% fair, 3% poor | n/a |
| Tam et al., 2017 | 795 (606) | 25 | n/a | Good to Excellent QoL (n=522, 88%) | P=0.978 | n/a |
|
| ||||||
| QOLRAD | ||||||
|
| ||||||
| Louie et al., 2011 | 58 (55) | 15 | 5 | 6 | P<0.001 | P<0.001* |
| Qureshi et al., 2013 | 21 (14) | 13 | 4.09 | 6.04 | P<0.0001 | n/a |
| Merzilikin et al., 2017 | 137 (59) | 60 | 4 | 6.5 | P=0.0005 | n/a |
| Hazebroek et al., 2008 (ANZ Journal of Surgery) | 40 (37) | 12 | 3-4 | 5-6 | P<0.001 | P<0.001† |
| Hazebroek et al., 2008 (Diseases of the Oesophagus) | 35 (30) | 43 | 3.98 | 6.04 | P<0.001 | P<0.001‡ |
| Stiven et al., 2013 | 114 (94) | 12 | 3.7 | 5.5 | P<0.001 | n/a |
| Ng et al., 2009 | 28 | 6 | 3.65§ 3,72¦ |
5.29§ 6.27¦ |
n/a | n/a |
| Parker et al., 2015 | 267 | 15.8 11.3 n/a |
4.07 (mean) | 7 (mean) | P<0.001 | n/a |
|
| ||||||
| GIQLI | ||||||
|
| ||||||
| Chen et al., 2018 | 69 (54) | 114 | n/a | 117 | Excellent or good in 83% | n/a |
| Dallemagne et al., 2011 | 85 (64) | 118 | n/a | NRCR 114 RCR 120 |
n/a | n/a |
| Targarona et al., 2013 | 77 (37) | 108 | n/a | NR 127 CR 97.5 RR 112 |
P=0.005 | n/a |
| Zhu et al., 2011 | 30 (30) | 24 | 85.7 | 107.9 | P<0.001 | n/a |
| Zugel et al., 2009 | 26 (20) | 12 (24 radiological) | 87 | 111 | NS (111) | n/a |
| Gibson et al., 2013 | 100 (92) | 24 | 87.8 | 109.1 | P=0.03 | n/a |
| Furtado et al., 2016 | 100 | 27 | 89 | 108 | P<0.001 | n/a |
|
| ||||||
| SF-36 | ||||||
|
| ||||||
| Tam et al., 2017 | 795 (606) | 25 | n/a | Good to excellent QoL (n=522, 88%) |
P=0.005 (PCS) P=0.264 (MCS) |
n/a |
| Koetje et al., 2015 | 126 (91) | 24 | n/a | Improvement across all groups | P<0.001 | PCS: P<0.001-0.044‡ MCS: variable significance‡ |
| Velanovich et al., 2001 | 44 (39) | 24 | n/a | Quality of results not suitable to display | PCS (P=0.02, significant) in LS group | n/a |
|
| ||||||
| GSRS | ||||||
|
| ||||||
| Parmeswaran et al., 2006 | 49 (31) | 19 | Pain 3.67 Reflux 4.53 Indigestion 3.74 |
Pain 1.79 Reflux 1.41 Indigestion 2.69 |
P<0.001 for all | n/a |
*At 1 year, †at all post-operative time periods 5 weeks, 6 months, 12 months, ‡at all post-operative time periods 3 months, 6 months, 12 months, 18 months, 24 months, §Bougie, ¦No bougie. NS: Not significant at 3 months, MU: Mesh used, NM: No Mesh, NR: No recurrence, LS: Laparoscopic surgery, OS: Open surgery, CR-:Clinical recurrence; RR: Radiological recurrence, NRCR: Non-reinforced crural repair, RCR: Reinforced crural repair, GERD-HRQL: Gastro-Oesophageal Reflux Disease-Health-Related Quality of Life, QOLRAD: Quality of Life in Reflux and Dyspepsia, QOL: Quality of life, SF: Short Form health surveys, GIQLI: Gastrointestinal Quality of Life Index, GSRS: Gastrointestinal Symptom Rating Scale, n/a: Not available