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. 2021 Oct 1;16(10):e0257607. doi: 10.1371/journal.pone.0257607

Table 5. Impact of interventions on short physical performance battery in heart failure patients.

SPPB HIIT CRT CG Within-group difference (post minus pre) Between-group difference
pre (n = 8) post (n = 8) pre (n = 5) post (n = 5) pre (n = 5) post (n = 5) Δ HIITMD (95% CI) Δ CRTMD (95% CI) Δ CG MD (95% CI) HIIT vs. CRT HIIT vs. CG CTR vs. CG
Balance test
Score [Q1-Q3] 4.0 [2.5–4.0] 4.0[4.0–4.0] 4.0 [3.0–4.0] 4.0 [4.0–4.0] 4.0 [4.0–4.0] 4.0 [4.0–4.0] - - - 0.046*
Gait test
Score [Q1-Q3] 3.5 [3.0–4.0] 3.5 [3.0–4.0] 3.0 [3.0–4.0] 4.0 [3.0–4.0] 3.0 [3.0–4.0] 4.0 [3.0–4.0] - - - 0.739
Seconds (95% CI) 3.6 ± 0.6 (3.1 to 4.1) 3.7 ± 0.9 (2.9 to 4.4) 3.5 ± 0.6 (2.8 to 4.2) 3.4 ± 0.6 (2.7 to 4.1) 3.6 ± 0.7 (2.7 to 4.5) 3.4 ± 0.7 (2.6 to 4.2) 0.0 (-0.8 to 0.8) -0.1 (-1.1 to 0.9) -0.2 (-1.2 to 0.8) -0.2 (-1.1 to 0.6) -0.2 (-1.0 to 0.7) 0.0 (-0.9 to 1.0)
Chair stand test
Score [Q1-Q3] 2.5 [2.0–3.0] 3.0 [2.3–3.8] 2.0 [1.0–3.5] 3.0 [3.0–4.0] 3.0 [2.0–3.3] 3.0 [2.5–4.0] - - - 0.083
Seconds (95% CI) 13.5 ± 2.0 (11.8 to 15.1 12.8 ± 2.4 (10.8 to 14.8) 14.3 ± 2.9 (10.7 to 18.0) 11.0 ± 1.4(9.3 to 12.7) 12.9 ± 1.6 (11.0 to 14.9) 12.6 ± 2.1 (10.0 to 15.3) -0.6 (-3.1 to 1.9) -3.3 (-6.5 to -0.2)* -0.3 (-3.4 to 2.9) -0.5 (-3.1 to 2.1) -0.4 (-3.0 to 2.2) 0.1 (-2.8 to 3.0)
Total SPPB
Score [Q1-Q3] 10.0 [8.3;10.8] 11.0 [9.3;11.0] 10.0 [8.0;10.0] 11.0 [10.0;12.0] 10.0 [9.5;11.0] 11.0 [10.0;11.5] - - - 0.008*

SPPB, short physical performance battery; HIIT, high-intensity interval training; CRT, circuit-resistance training; CG, control group. Values are expressed as median and interquatile range (Q1-Q3) for scores and mean ± standard deviation (SD), mean difference (MD) and 95% CI (confidence interval) for seconds. Comparisons between groups were analyzed by mixed ANOVA for parametric distribution, while Friedman two-way test was applied for the difference among groups (HIIT, CRT and CG) which does not allow the comparison between groups pairwise.

*p ≤0.05.