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. 2021 Oct 1;16(10):e0254985. doi: 10.1371/journal.pone.0254985

Table 3. A comparison of IL-22:Fc treated and sham animals after acute lung injury with high dose LPS.

Cytokine IL-22:Fc Treated (pg/mL) Sham (pg/mL) p-value
Interleukin-1α 69.39 ± 5.91 28.14 ± 5.40 <0.001
Interleukin-1β 3.48 ± 1.25 10.05 ± 3.26 0.04
Interleukin-2 7.33 ± 0.83 0.26 ± 0.45 <0.001
Interleukin-3 1.07 ± 0.02 1.05 ± 0.06 0.37
Interleukin-4 1.09 ± 0.09 0.90 ± 0.12 0.10
Interleukin-5 7.86 ± 1.14 0.29 ± 0.29 <0.001
Interleukin-7 1.75 ± 0.18 2.14 ± 1.16 0.37
Interleukin-9 311.8 ± 38.17 79.57 ± 15.47 <0.001
Interleukin-12 (p40) 7.13 ± 1.89 3.27 ± 1.04 0.049
Interleukin-12 (p70) 1.95 ± 1.00 2.88 ± 0.93 0.19
Interleukin-13 10.56 ± 1.49 7.92 ± 1.92 0.15
Interleukin-15 6.10 ± 1.02 1.85 ± 0.57 0.002
Interleukin-17 2.28 ± 0.56 12.34 ± 4.67 0.03
Eotaxin 4.63 ± 2.43 21.59 ± 0.09
Interferon-γ 8.08 ± 2.18 103.9 ± 92.04 0.16
Granulocyte-Macrophage Colony-Stimulating Factor 0.00 ± 0.00 0.38 ± 0.38 0.17
Interferon-γ-Induced Protein-10 118.40 ± 43.72 616.90 ± 171.1 0.01
Keratinocyte Chemoattractant/Growth Regulated Oncogene 19.54 ± 3.08 35.89 ± 12.54 0.11
Monocyte Chemoattractant Protein 14.66 ± 7.16 34.20 ± 15.08 0.13
Macrophage Inflammatory Protein-1α 45.99 ± 7.56 73.96 ± 15.40 0.07
Macrophage Inflammatory Protein-1β 19.42 ± 7.63 70.89 ± 21.44 0.02
Macrophage Inflammatory Protein-2 28.63 ± 5.43 16.54 ± 7.99 0.11
Monocyte Induced by Interferon-γ 100.60 ± 35.47 906.00 ± 295.40 0.01
Macrophage Colony-Stimulating Factor 2.89 ± 1.02 1.02 ± 0.41 0.049
C-X-C Motif Chemokine 5 (LIX) 0.00 ± 0.00 0.00 ± 0.00 0.99
Vascular Endothelial Growth Factor 12.18 ± 3.03 12.64 ± 5.22 0.47