. 2021 Apr 23;64(10):6937–6948. doi: 10.1021/acs.jmedchem.1c00484

Table 1. From TM5/6 Prototypes to a Drug-Like Finalist Peptide^a.

peptide		sequence^b	residues
prototypes¹⁸	TM5-Tat	ETYLMFWIGVTSVLLLFIVYAYMYILWGRKKRRQRRR	37
	Tat-TM6	GRKKRRQRRRKTLVLILVVLIICWGPLLAIMVYDVF	36
optimized candidate		wliymyayvaGilkrw	16

A detailed list of all peptides used in the various rounds of the optimization process is given in Tables S1–S4.

Upper and lower case denote l- and d-residues, respectively.

Table 1. From TM5/6 Prototypes to a Drug-Like Finalist Peptidea.